Volume 11, Number 4—April 2005
Dispatch
Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells
Wee-Lee Koh* and Mah-Lee Ng*
Table 2
Comparison of gene expression changes between microarray and qRT-PCR in A172 cells infected with West Nile virus*
| Gene | Gene name | Microarray fold change | RT-PCR fold change |
|---|---|---|---|
| ARHI | DIRAS family, GTP-binding RAS-like 3 | –2.72 | –2.55 |
| ATP5J | ATP synthase, mitochondrial F0 complex, subunit F6 | –2.11 | –2.60 |
| CEB1 | Hect domain and RLD 5 | 2.32 | 42.22 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | –1.97 | –2.14 |
| DUSP1 | Dual specificity phosphatase 1 | 1.92 | 5.66 |
| EGR1 | Early growth response 1 | 4.79 | 8.57 |
| EIF4G2 | Eukaryotic translation initiation factor 4 γ, 2 | –2.11 | –7.77 |
| FLJ13855 | Hypothetical protein FLJ13855 | 2.05 | 3.85 |
| FOSL1 | FOS-like antigen 1 | 2.08 | 6.50 |
| IFITM1 | Interferon-induced transmembrane protein 1 (9-27) | 12.03 | 527.61 |
| LTA4H | Leukotriene A4 hydrolase | –2.02 | –8.10 |
| RPL5 | Ribosomal protein L5 | –2.97 | –9.03 |
| RPL7A | Ribosomal protein L7a | –2.03 | –3.42 |
| RPLP0 | Ribosomal protein, large, P0 | –2.15 | –1.52 |
| TFPI2 | Tissue factor pathway inhibitor 2 | 5.21 | 11.58 |
*qRT-PCR, quantitative reverse transcription–polymerase chain reaction.
