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Volume 11, Number 6—June 2005

Research

Community-associated Methicillin-resistant Staphylococcus aureus, Canada

Michael R. Mulvey*Comments to Author , Laura MacDougall†‡, Brenda Cholin§, Greg Horsman¶, Melanie Fidyk#, Shirley Woods**, and the Saskatchewan CA-MRSA Study Group
Author affiliations: *National Microbiology Laboratory, Winnipeg, Manitoba, Canada; †British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada; ‡Health Canada, Ottawa, Ontario, Canada; §Prairie North Health Region, North Battleford, Saskatchewan, Canada; ¶Saskatchewan Health Provincial Laboratory, Regina, Saskatchewan, Canada; #Kelsey Trail Health Region, Nipawin, Saskatchewan, Canada; **Northern Intertribal Health Authority, Prince Albert, Saskatchewan, Canada

Main Article

Table 2

Antimicrobial susceptibilities of the different clonal groups identified using pulsed-field gel electrophoresis

Antimicrobial agent Clonal group A (n = 55)
Clonal group B (n = 126)
MIC50 (mg/L) MIC90 (mg/L) % resistant Range MIC50 (mg/L) MIC90 (mg/L) % resistant Range
Oxacillin 16 32 100 4–64 16 32 100 4–64
Cefazolin 32 32 75 4–32 16 32 31 2–32
Ciprofloxacin 32 ≥32 86 0.25–≥32 0.25 0.25 0 0.25–0.5
Clindamycin <0.25 ≥8 11 <0.25–≥8 <0.25 <0.25 1.6 <0.25–≥8
Erythromycin >8 ≥8 87 <0.25–≥8 <0.25 ≥8 40 <0.25–≥8
Gentamicin >16 ≥16 64 <0.5–≥16 <0.5 <0.5 0 <0.5
Rifampin <0.25 <0.25 3.6 <0.25–≥4 <0.25 <0.25 0 <0.25
Tetracycline 16 ≥16 55 <2–≥16 <2 <2 0 <2
Trimethoprim/sulfamethoxazole <0.25 0.5 5.5 <0.25 <0.25 <0.25 0 <0.25
Vancomycin 1.0 1.0 0 1.0 1.0 1.0 0 0.5-1.0
Linezolid 4.0 4.0 0 4.0 2.0 4.0 0 1.0-4.0
Mupirocin ≥128 ≥128 58 ≥128 ≥128 ≥128 55.6 <0.25–≥128
Fusidic acid ≥8 ≥8 100 ≥8.0 0.12 0.25 0 0.12–0.25

Main Article

1Members of the Saskatchewan CA-MRSA Study Group: N. Antonishyn, Provincial Laboratory Saskatchewan Health, Regina, SK; T. Du, National Microbiology Laboratory, Winnipeg, MB; J. Embil, University of Manitoba, Winnipeg, MB; A. Graessli, University of Manitoba, Winnipeg, MB; J. Irvine, Keewatin Yatthe & Mamaweetan Churchill Regional Health Authority, La Ronge, SK; M. Khan, Kelsey Trail Health Region, Melfort, SK; S. Martin, Kelsey Trail Health Region, Nipawin, SK; R. McDonald, Provincial Laboratory Saskatchewan Health, Regina, SK; M. Nsungu, Northern Intertribal Health Authority, Prince Albert, SK; S. Paton, Public Health Agency of Canada, Ottawa, ON; C. Celin, National Microbiology Laboratory, Winnipeg, MB; D. Spreitzer, National Microbiology Laboratory, Winnipeg, MB; D. Stockdale, Keewatin Yatthe & Mamaweetan Churchill Regional Health Authority, La Ronge, SK.

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