Volume 11, Number 8—August 2005
Cost-Benefit of Stockpiling Drugs for Influenza Pandemic
|Overall attack rate, %†||25||15–35|
|Probability of pandemic (per year)||3||1–10|
|Adult workdays lost, by age, y|
|Average hospital stay (days) by age, y|
|Patients seeking medical care within 48 h, %||80||70–90|
|Efficacy of antiviral prophylaxis, %|
|Preexposure prophylaxis (50 days)||71||57–85|
|Postexposure prophylaxis (7 days)||36||25–47|
|Efficacy of antiviral therapy, %|
|Reduction in hospitalizations||59||30–70|
|Reduction in antimicrobial drug use
|Reduction in lost workdays under treatment||1||0.5–1.5|
*Complete list and references available in online Appendix.
†Population attack rate was calculated by stratifying the population by age and risk and applying age- and risk-specific attack rates and ranges (Appendix).