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Volume 12, Number 10—October 2006

Research

Human Prion Disease and Relative Risk Associated with Chronic Wasting Disease

W. John Pape†, Jeri Forster*, C. Alan Anderson‡§, Patrick Bosque‡¶, Patrick Bosque‡¶, Michael Miller#, and Samantha MaWhinney
Author affiliations: *University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA; †Colorado Department of Public Health and Environment, Denver, Colorado, USA; ‡University of Colorado School of Medicine, Denver, Colorado, USA; §Denver Veteran's Affairs Medical Center, Denver, Colorado, USA; ¶Denver Health Medical Center, Denver, Colorado, USA; #Colorado Division of Wildlife, Fort Collins, Colorado, USA

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Table 3

Univariate relative risk estimates of available risk factors for Creutzfeldt-Jakob disease, data from Colorado death certificates, 1979–2001*

Covariate RR (95% CI), N = 506,335, events = 65
Age at death p = 0.029
Units = 10 y 0.87 (0.78–0.99)
CWD county† p = 0.61
No 1.0
Yes 0.83 (0.41–1.68)
Death year† p = 0.54
Units = 5 y 0.95 (0.79–0.13)
Sex p = 0.90
Male 1.0
Female 0.97 (0.60–1.58)
ICD-10 p = 0.83
No 1.0
Yes 1.07 (0.56–2.05)
Marital status p = 0.0094
Widowed 1.0
Divorced 0.80 (0.23–2.85)
Married 2.86 (1.51–5.42)
Single 2.19 (0.86–5.57)
Unknown –‡
Race p = 0.94
White 1.0
Nonwhite 2.87 (0.40–20.6)

*RR, relative risk; CI, confidence interval; CWD, chronic wasting disease.
†Primary predictor .
‡Insufficient events.

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