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Volume 12, Number 10—October 2006

Research

Human Prion Disease and Relative Risk Associated with Chronic Wasting Disease

W. John Pape†, Jeri Forster*, C. Alan Anderson‡§, Patrick Bosque‡¶, Patrick Bosque‡¶, Michael Miller#, and Samantha MaWhinney
Author affiliations: *University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA; †Colorado Department of Public Health and Environment, Denver, Colorado, USA; ‡University of Colorado School of Medicine, Denver, Colorado, USA; §Denver Veteran's Affairs Medical Center, Denver, Colorado, USA; ¶Denver Health Medical Center, Denver, Colorado, USA; #Colorado Division of Wildlife, Fort Collins, Colorado, USA

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Table 4

Results for primary predictors from multivariable analyses for CJD and expanded event definitions, data from Colorado death certificates, 1979–2001*

Covariate CJD, N = 506,335, events = 65
RR (95% CI) Expanded age 12–55 y, N = 89,033, events = 339
RR (95% CI) Expanded, N = 506,335, events = 1,911
RR (95% CI)
CWD-endemic county p = 0.55 p = 0.75 p = 0.48
No 1.0 1.0 1.0
Yes 0.81 (0.40, 1.63) 0.95 (0.69–1.31) 1.05 (0.93–1.18)
Death year p = 0.48 p = 0.15 p < 0.0001
Units = 5 y 0.92 (0.73–1.16) 0.93 (0.84–1.03) 0.81 (0.77–0.84)

*CJD, Creutzfeldt-Jakob disease; RR, relative risk; CI, confidence interval; CWD, chronic wasting disease.

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