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Volume 12, Number 10—October 2006

Research

Novel Chikungunya Virus Variant in Travelers Returning from Indian Ocean Islands

Philippe Parola*†1, Xavier de Lamballerie‡§1, Jacques Jourdan¶, Clarisse Rovery*, Véronique Vaillant#, Philippe Minodier*, Philippe Brouqui*†, Antoine Flahault**, Didier Raoult†‡Comments to Author , and Rémi Charrel‡§
Author affiliations: *Hôpital Nord, Marseilles, France; †Unité des Rickettsies, Marseilles, France; ‡Fédération de Microbiologie Clinique Hôpital de la Timone, Marseilles, France; §Unité des Virus Emergents, Faculté de Médecine, Marseilles, France; ¶Centre Hospitalier Universitaire, Nîmes, France; #Institut de Veille Sanitaire, Saint-Maurice, France; **Université Pierre et Marie Curie, Paris, France

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Figure 3

Phylogenetic analysis of chikungunya virus (CHIKV) isolates based on a 1,044-nucleotide (nt) fragment between nt 10243 and 11286 (numbered after strain Ross [accession no. AF490259]) in the E1 gene. Distances and groupings between the 3 Indian Ocean isolates and 18 isolates previously characterized (23) were determined by the Jukes-Cantor algorithm and neighbor-joining method with the MEGA software program (25). Bootstrap values >75% are indicated and correspond to 500 replications. The main

Figure 3. Phylogenetic analysis of chikungunya virus (CHIKV) isolates based on a 1,044-nucleotide (nt) fragment between nt 10243 and 11286 (numbered after strain Ross [accession no. AF490259]) in the E1 gene. Distances and groupings between the 3 Indian Ocean isolates and 18 isolates previously characterized (23) were determined by the Jukes-Cantor algorithm and neighbor-joining method with the MEGA software program (25). Bootstrap values >75% are indicated and correspond to 500 replications. The main evolutionary lineages, East/Central African (brown), eastern/southern Africa (red), West African (blue), and Asian (yellow), are indicated. The Indian Ocean sublineage is indicated in orange. Boldface indicates sequence determined in this study.

Main Article

1These authors contributed equally to this study.

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