Volume 12, Number 2—February 2006
Letter
Borrelia burgdorferi and Anaplasma phagocytophilum Coinfection
Micha Loebermann*, Volker Fingerle†, Matthias Lademann*, Carlos Fritzsche*, and Emil C. Reisinger*
Table
Results of serologic tests at diagnosis and during follow-up*
| Time (d) after onset of symptoms | Anaplasma (Ehrlichia) phagocytophilum (IFA)† |
Borrelia burgdorferi (ELISA)‡ |
Borrelia burgdorferi (Immunoblot)§ |
|||
|---|---|---|---|---|---|---|
| IgM | IgG | IgM | IgG | IgM | IgG | |
| 6 | Negative (<1:20) | Negative (<1:32) | Negative | Negative | Negative | Negative |
| 10 | ND | ND | Positive | Negative | ND | ND |
| 28 | Positive (1:40) | Negative (1:32) | Positive | Negative | Positive | Negative |
| 107 | Positive (1:20) | Negative (<1:32) | Positive | Negative | Positive | Negative |
| 380 | Negative (<1:20) | Negative (<1:32) | Equivocal | Negative | Positive | Negative |
*Symptoms (fever, headache, myalgia) started 6 days before presentation. IFA, immunofluorescent assay; ELISA, enzyme-linked immunosorbent assay; Ig, immunoglobulin; ND, not done.
†Genzyme Virotech, Germany. Positive titers: IgM >1:20, IgG >1:64.
‡Behring, Germany.
§In-house Immunoblot, Max von Pettenkofer-Institut, Munich, Germany.
