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Volume 12, Number 3—March 2006
Research

Self-medication with Antimicrobial Drugs in Europe

Larissa Grigoryan*Comments to Author , Flora M. Haaijer-Ruskamp*, Johannes G.M. Burgerhof*, Reli Mechtler†, Reginald Deschepper‡, Arjana Tambic-Andrasevic§, Retnosari Andrajati¶, Dominique L. Monnet#, Robert Cunney**, Antonella Di Matteo††, Hana Edelstein‡‡, Rolanda Valinteliene§§, Alaa Alkerwi¶¶, Elizabeth A. Scicluna##, Pawel Grzesiowski***, Ana-Claudia Bara†††, Thomas Tesar‡‡‡, Milan Cizman§§§, Jose Campos¶¶¶, Cecilia Stålsby Lundborg###, and Joan Birkin****
Author affiliations: *University Medical Center Groningen, Groningen, the Netherlands; †University of Linz, Linz, Austria; ‡Vrije Universiteit Brussel, Brussels, Belgium; §University Hospital for Infectious Diseases, Zagreb, Croatia; ¶Charles University, Prague, Czech Republic; #Statens Serum Institut, Copenhagen, Denmark; **Health Protection Surveillance Centre, Dublin, Ireland; ††Consorzio Mario Negri Sud, Chieti, Italy; ‡‡Ha'Emek Medical Center, Afula, Israel; §§Institute of Hygiene, Vilnius, Lithuania; ¶¶Directorate of Health, Luxembourg, Luxembourg; ##St Luke's Hospital, G'Mangia, Malta; ***National Institute of Public Health, Warsaw, Poland; †††Max Planck Institute for Demographic Research, Rostock, Germany; ‡‡‡Comenius University, Bratislava, Slovakia; §§§University Medical Centre, Ljubljana, Slovenia; ¶¶¶Instituto de Salud Carlos III, Madrid, Spain; ###Karolinska Institutet, Göteborg, Sweden; ****Nottingham City Hospital, Nottingham, United Kingdom

Main Article

Table 2

Actual use of systemic antimicrobial drugs in the last 12 months and at-risk self-medication in 19 European countries

Country (region in country) Rate per 1,000 respondents (95% confidence interval)
Actual self-medication Prescribed use Intended self-medication Storage*
(conservative estimate) Storage†
(maximum estimate)
Countries with response rate >40%
Northern and western
The Netherlands (Twente) 1 (0.2–4) 152 (134–170) 85 (71–101) 10 (6–17) 36 (28–46)
Sweden (Vastmanland) 4 (0.9–12) 135 (109–161) 118 (94–143) 14 (7–26) 43 (29–60)
Denmark (Funen, Aarhus, Copenhagen‡) 7 (4–12) 172 (154–189) 132 (116–147) 42 (33–52) 84 (72–97)
Luxemburg (whole country) 9 (3–19) 288 (252–324) 83 (62–107) 90 (69–114) 132 (106–158)
Belgium (East Flanders, Flemish Brabant) 9 (5–15) 222 (201–242) 80 (67–95) 71 (59–84) 123 (107–138)
Southern
Malta (whole country) 56 (38–79) 422 (380–465) 228 (192–264) 156 (125–186) 269 (232–306)
Eastern
Czech Republic (Hradec Krlov) 7 (3–13) 253 (228–279) 179 (156–201) 45 (33–58) 64 (51–80)
Slovakia (Middle Slovakia region) 42 (27–63) 569 (527–612) 324 (284–365) 192 (159–225) 302 (263–340)
Romania (Dolj) 198 (160–235) 307 (263–351) 431 (383–478) 200 (162–238) 321 (277–365)
Countries with response rate <40%§
Northern and western 52 (33–77)
Austria (Upper Austria) 9 (2–23) 159 (124–195) 73 (49–103) 34 (19–55) 52 (33–77)
United Kingdom (Nottinghamshire) 12 (5–23) 221 (189–254) 166 (137–195) 33 (21–49) 74 (56–97)
Ireland (Cork) 14 (7–25) 353 (320–386) 150 (125–176) 29 (19–43) 100 (80–123)
Southern
Israel (Northern Israel) 15 (6–31) 330 (287–374) 187 (150–223) 120 (91–149) 236 (197–274)
Italy (Abruzzo) 62 (33–103) 512 (444–580) 243 (185–301) 379 (314–445) 569 (502–636)
Spain (autonomous community of Madrid) 152 (103–201) 315 (251–379) 314 (249–380) 260 (200–320) 500 (431–569)
Eastern
Slovenia (Ljubljana region) 17 (10–26) 293 (266–320) 280 (253–307) 119 (100–137) 183 (160–205)
Croatia (Zagreb county) 31 (19–48) 439 (399–478) 205 (172–237) 130 (103–156) 212 (179–244)
Poland (Pomorskie) 33 (23–47) 199 (172–225) 115 (94–136) 69 (53–87) 137 (115–160)
Lithuania (Klaipeda, Rietavas) 210 (181–239) 275 (243–308) 449 (412–486) 177 (149–204) 333 (299–367)

*Included only those respondents who stored antimicrobial drugs and had not taken the same antimicrobial drugs for a prescribed course in the previous 12 months.
†Including all respondents who stored antimicrobial drugs.
‡Although Copenhagen has population >750,000, both self-medication and prescribed use of antimicrobial drugs were not significantly different between the sample of Copenhagen and sample of the other 2 Danish counties (χ2 tests).
§The rates for these countries should be interpreted as first rough estimates.

Main Article

1A copy of the questionnaire is available from the corresponding author on request.

2The adjusted estimates for each country are available from the corresponding author on request.

3Results are available from the corresponding author on request.

Page created: January 27, 2012
Page updated: January 27, 2012
Page reviewed: January 27, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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