Volume 13, Number 10—October 2007
Dispatch
Super-Sentinel Chickens and Detection of Low-Pathogenicity Influenza Virus
Philip I. Marcus*
, Theodore Girshick†, Louis van der Heide*, and Margaret J. Sekellick*
, Theodore Girshick†, Louis van der Heide*, and Margaret J. Sekellick*Table 2
Influenza A virus infectious particle equivalents (IPE) in tracheal swabs from sentinel chickens given water or water + interferon and infected naturally*
| Day postinfection | Water (IPE/mL) | Water + interferon† (IPE/mL) |
|---|---|---|
| 2 | 1,112 ± 1,353‡ | 760 ± 632 |
| 4 | 1,234 ± 764 | 463 ± 484 |
| 10 | 1,325 ± 398 | 2,113 ± 1,834 |
*Each cage contained 2 overtly infected birds and 8 cage mates as sentinels. Only sentinel birds are reported. Chickens were 3 weeks old at the start.
†Recombinant chicken interferon-α in water at 2,000 U/mL (5).
‡Mean ± SD, n = 8. Qualitative real-time reverse transcriptase–PCR analysis with influenza A virus standard: IPE/mL.
