Volume 13, Number 10—October 2007
Research
Rapid Increase of Genetically Diverse Methicillin-Resistant Staphylococcus aureus, Copenhagen, Denmark
Table 1
Demographics, infection types, and distribution of MRSA types in 143 cases of MRSA*
| Community onset, community risk | Community onset, no risk | Hospital acquired in Denmark | Community onset, healthcare associated | Imported | |
|---|---|---|---|---|---|
| No. cases | 30 | 35 | 37 | 36 | |
| Male, % | 67 | 46 | 57 | 42 | |
| Median age, y (range) | 27 (1–74) | 32 (0–90) | 80 (28–94) | 82 (6–95) | |
| Carrier, no. |
8 |
1 |
2 |
2 |
4† |
| Type of infection, no. | |||||
| SSTI | 22 | 29 | 17 | 23 | |
| Blood | 0 | 0 | 2 | 2 | |
| Deep-seated abscess, no. | 0 | 1 | 5 | 3 | |
| UTI | 0 | 4 | 8 | 5 | |
| LRTI |
0 |
0 |
3 |
1 |
1† |
| Four most common CCs (87% of all isolates) | |||||
| CC 8, % | 23 | 34 | 81 | 69 | |
| t008, no. | 3 | 7 | 0 | 2 | |
| t024, no. | 3 | 5 | 28 | 20 | |
| CC 80, % | 20 | 34 | 3 | 0 | |
| CC 30, % | 50 | 6 | 0 | 0 | |
| CC 5, % | 3 | 11 | 5 | 8 | |
| Other MLST types,% | 4 | 15 | 11 | 23 | |
| PVL positive, % | 83 | 80 | 8 | 17 | |
| SCCmec IV, % | 93 | 89 | 89 | 81 | |
*MRSA, methicillin-resistant Staphylococcus aureus; SSTI, skin and soft tissue infection; UTI, urinary tract infection; LRTI, lower respiratory tract infection; CC, clonal complex; MLST, multilocus sequence typing; PVL, Panton-Valentine leukocidin; SCC, staphylococcal chromosome cassette.
†A t037/ST239-III was imported from Greece, where this MRSA is common (20); ST239 is closely related to ST8 and is the well-known pandemic Brazilian/Hungarian clone (21); t041/ST111 was imported from an Italian hospital; t003/ST225-II (New York clone) was imported from Germany; t354/ST22-IV, a variant of EMRSA15, was imported from Lanzarote (Spain); and t067/ST125-I was imported from Spain.
