Volume 13, Number 11—November 2007
Research
Role of Terrestrial Wild Birds in Ecology of Influenza A Virus (H5N1)
Adrianus C.M. Boon*1, Matthew R. Sandbulte*1, Patrick Seiler*, Richard J. Webby*, Thaweesak Songserm†, Yi Guan‡, and Robert G. Webster*
Table 1
Influenza A virus titers in oropharyngeal and cloacae swabs of infected birds*
| Species |
Virus |
Mortality rate, % |
Virus titer (EID50/mL) in swabs from infected animals |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Day 2 |
Day 4 |
Day 6 |
||||||||
| T | C | T | C | T | C | |||||
| Sparrow |
A/DK/TH/144/05 | 100 | 2.4 | 1.7 | 4.7 | 4.1 | –† | – | ||
| A/Q/TH/551/05 | 100 | 1.0 | <1 | 1.5 | 1.3 | 3.1 | 1.0 | |||
| A/CM/HK/645/06 | 66 | 2.6 | 0.8 | 2.3 | 2.1 | 1.6 | 1.1 | |||
| A/JW/HK/1038/06 |
100 |
2.1 |
<1 |
2.7 |
3.3 |
– |
– |
|||
| Day 2 |
Day 4 |
Day 6 |
||||||||
| T |
C |
T |
C |
T |
C |
|||||
| Starling |
A/DK/TH/144/05 | 0 | 3.8 | 0.8 | 3.3 | <1 | 2 | <1 | ||
| A/Q/TH/551/05 | 0 | ND | ND | ND | ND | ND | ND | |||
| A/CM/HK/645/06 | 0 | 3.3 | 0.8 | 3.6 | 1 | 1.7 | 1.5 | |||
| A/JW/HK/1038/06 |
0 |
2.5 |
1 |
2 |
<1 |
1.8 |
<1 |
|||
| Day 3 |
Day 5 |
Day 7 |
||||||||
| T |
C |
T |
C |
T |
C |
|||||
| Pigeon | A/DK/TH/144/05 | 0 | <1 | <1 | <1 | <1 | <1 | <1 | ||
| A/Q/TH/551/05 | 0 | <1 | 0.5 | 0.8 | <1 | <1 | <1 | |||
| A/CM/HK/645/06 | 0 | 1.9 | <1 | 1.4 | <1 | <1 | <1 | |||
| A/JW/HK/1038/06‡ | 0 | 0.5 | <1 | 0.4 | <1 | <1 | <1 | |||
*EID50, 50% egg infectious dose; T, oropharyngeal swab; C, cloacal swab; ND, not done.
†Birds did not survive the infection.
‡Swabs were taken on days 3, 6, and 10 after infection.
