Volume 13, Number 11—November 2007
Research
Methamphetamine Use and Methicillin-Resistant Staphylococcus aureus Skin Infections
Adam L. Cohen*
, Carrie Shuler*†, Sigrid McAllister*, Gregory E. Fosheim*, Michael G. Brown‡, Debra Abercrombie§, Karen Anderson*, Linda K. McDougal*, Cherie Drenzek†, Katie Arnold†, Daniel Jernigan*, and Rachel Gorwitz*
, Carrie Shuler*†, Sigrid McAllister*, Gregory E. Fosheim*, Michael G. Brown‡, Debra Abercrombie§, Karen Anderson*, Linda K. McDougal*, Cherie Drenzek†, Katie Arnold†, Daniel Jernigan*, and Rachel Gorwitz*Table 2
Risk factors for MRSA skin and soft tissue infection*
| Risk factors | Case-patients, no. (%) | Controls, no. (%) | Crude OR (95% CI) | Adjusted OR† (95% CI) |
|---|---|---|---|---|
| Drug use and medical history | ||||
| Recent skin infection‡ | 34 (42.0) | 22 (7.8) | 8.41 (4.54–15.59) | 7.92 (4.10–15.28) |
| Recent methamphetamine use‡ | 8 (9.9) | 5 (1.8) | 5.64 (1.80–17.69) | 5.10 (1.55–16.79) |
| Antimicrobial agents within 6 months | 40 (49.4) | 114 (40.1) | 1.43 (0.87–2.34) | 1.52 (0.89–2.60) |
| Recent hospitalization, surgery, or dialysis‡ | 8 (9.9) | 27 (9.5) | 1.06 (0.46–2.44) | 1.24 (0.51–2.97) |
| Diabetes | 10 (12.4) | 23 (8.1) | 1.61 (0.73–3.57) | 2.03 (0.83–4.98) |
| Liver disease |
1 (1.2) |
9 (3.2) |
0.38 (0.05–3.07) |
0.59 (0.70–4.91) |
| Contact exposure | ||||
| Household contact with someone with skin infection | 21 (25.9) | 27 (9.5) | 3.26 (1.72–6.17) | 3.19 (1.58–6.48) |
| Crowding (>1 person/bedroom) | 44 (54.3) | 111 (39.1) | 2.06 (1.22–3.45) | 1.78 (1.004–3.15)§ |
| Recent sexual contact‡ | 48 (59.3) | 182 (64.1) | 0.85 (0.51–1.42) | 0.68 (0.38–1.22) |
| Recent sexual contact with someone with skin infection‡ | 7 (8.6) | 6 (2.1) | 4.28 (1.40–13.08) | 5.42 (1.68–17.50) |
| Recent contact sports‡ | 9 (11.1) | 11 (3.9) | 2.92 (1.17–7.31) | 1.37 (0.47–4.03) |
| Recent jail‡ |
4 (4.9) |
9 (3.2) |
1.46 (0.44–4.90) |
1.75 (0.48–6.42) |
| Hygiene practices | ||||
| Frequent skin picking | 17 (20.1) | 24 (8.5) | 2.77 (1.40–5.47) | 2.53 (1.22–5.23) |
| Bathe less than daily | 5 (6.2) | 31 (10.9) | 0.50 (0.19–1.34) | 0.56 (0.19–1.67) |
*MRSA, methicillin-resistant Staphylococcus aureus; OR, odds ratio; CI, confidence interval.
†All models are adjusted for age, sex, race, and methamphetamine use, except the model for methamphetamine use, which is adjusted only for age, sex, and race.
‡Recent = within the 3 months prior to survey.
§p = 0.048.
