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Volume 13, Number 11—November 2007

Research

Protection and Virus Shedding of Falcons Vaccinated against Highly Pathogenic Avian Influenza A Virus (H5N1)

Michael Lierz*Comments to Author , Hafez M. Hafez*, Robert Klopfleisch†, Dörte Lüschow*, Christine Prusas*, Jens P. Teifke†, Miriam Rudolf†, Christian Grund†, Donata Kalthoff†, Thomas Mettenleiter†, Martin Beer†, and Timm Harder†
Author affiliations: *Freie Universität, Berlin, Germany; †Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany;

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Figure 2

Immunohistochemical demonstration of influenza A virus antigen (red, see arrows) in numerous splenic macrophages of a falcon after challenge with 106.0 50% egg infectious doses of the highly pathogenic avian influenza strain A/Cygnus cygnus/Germany/R65/06 (H5N1). Avidin-biotin-peroxidase complex method. Bar = 25 μm.

Figure 2. Immunohistochemical demonstration of influenza A virus antigen (red, see arrows) in numerous splenic macrophages of a falcon after challenge with 106.0 50% egg infectious doses of the highly pathogenic avian influenza strain A/Cygnus cygnus/Germany/R65/06 (H5N1). Avidin-biotin-peroxidase complex method. Bar = 25 μm.

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