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Volume 13, Number 11—November 2007

Research

Protection and Virus Shedding of Falcons Vaccinated against Highly Pathogenic Avian Influenza A Virus (H5N1)

Michael Lierz*Comments to Author , Hafez M. Hafez*, Robert Klopfleisch†, Dörte Lüschow*, Christine Prusas*, Jens P. Teifke†, Miriam Rudolf†, Christian Grund†, Donata Kalthoff†, Thomas Mettenleiter†, Martin Beer†, and Timm Harder†
Author affiliations: *Freie Universität, Berlin, Germany; †Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany;

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Table 2

Excretion of infectious highly pathogenic avian influenza virus (H5N1) in vaccinated and control falcons after challenge

Vaccination status Excretion route* Days postchallenge†
0 1 2 4 7 11
Vaccinated Oropharyngeal <0.5 4.4 1.2 <0.5 <0.5 <0.5
Nonvaccinated Oropharyngeal <0.5 5.4 4.4 2.0 No data No data
Vaccinated Cloacal <0.5 <0.5 <0.5 <0.5 <0.5 <0.5
Nonvaccinated Cloacal <0.5 <0.5 3.0 2.7 No data No data

*Pooled samples of all birds in the group were examined.
†Data represent log10 of 50% egg infectious dose per mL.

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