Volume 13, Number 2—February 2007
Dispatch
Pneumocystis Pneumonia in HIV-positive Adults, Malawi1
Joep J.G. van Oosterhout*, Miriam K. Laufer†, M. Arantza Perez*, Stephen M. Graham*, Nelson Chimbiya*, Phillip C. Thesing*, Miriam J. Álvarez-Martinez‡, Paul E. Wilson‡, Maganizo Chagomerana*, Eduard E. Zijlstra*, Terrie E. Taylor*§, Christopher V. Plowe†
, and Steven R Meshnick‡
, and Steven R Meshnick‡Table 2
Outcomes in 95 episodes of suspected Pneumocystis pneumonia (PcP), Malawi, 2002–2004*
| Final diagnosis† | Clinical diagnosis‡ | No. episodes | IF | PCR | Follow-up data |
|---|---|---|---|---|---|
| Confirmed PcP | PcP | 2 | Pos | Pos | – |
| Confirmed PcP | PcP | 1 | Neg | Pos | – |
| Confirmed PcP | PcP | 1 | – | – | Death after 2 wk of PcP treatment (IS not done due to respiratory distress) |
| Confirmed PcP | Bronchiectasies | 1 | Neg | Pos | Death 1 wk after IS |
| Confirmed PcP | Tuberculosis | 1 | Neg | Pos | Improvement but short follow-up (2 wk) |
| Pneumocystis colonization/pulmonary KS | Pulmonary KS | 3§ | Neg | Pos | Death 23 wk after first IS |
| Pneumocystis colonization/tuberculosis | Tuberculosis | 3 | Neg | Pos | Recovery |
| Pneumocystis colonization/bacterial pneumonia | Bacterial pneumonia | 2 | Neg | Pos | Recovery |
| Pneumocystis colonization/unspecified respiratory illness | Unspecified respiratory illness | 2 | Neg | Pos | Recovery |
| Pneumocystis colonization/other diagnosis | Other diagnosis¶ | 1 | Neg | Pos | Recovery |
| Unspecified respiratory illness | PcP | 3 | Neg | Neg | – |
| Tuberculosis | Tuberculosis | 19 | Neg | Neg | – |
| Bacterial pneumonia | Bacterial pneumonia | 10 | Neg | Neg | – |
| Unspecified respiratory illness | Unspecified respiratory illness | 20 | Neg | Neg | – |
| Unspecified respiratory illness | Unspecified respiratory illness | 1 | Neg | NA | Recovery (18 wk follow-up) |
| Other diagnoses¶ | Other diagnoses¶ | 24 | Neg | Neg | – |
| Other diagnosis¶ | Other diagnosis¶ | 1 | Neg | NA | Recovery (>1 y follow-up) |
*IF, immunofluorescence stain; pos, positive; neg, negative; IS, induced sputum procedure; KS, Kaposi sarcoma.
†Diagnosis based on clinical evidence, IF, and PCR from an IS sample, and follow-up after episode.
‡Diagnosis based on clinical evidence and IF from an IS sample.
§Three episodes occurring in 1 person.
¶Among other diagnoses were sepsis, bronchitis, emphysema, pulmonary KS, and bronchiectasis.
