Volume 13, Number 2—February 2007
Research
Neutralizing Antibodies after Infection with Dengue 1 Virus
Gustavo Kourí*
, Mayling Alvarez*, Rosmari Rodriguez-Roche*, Lídice Bernardo*, Tibaire Montes†, Susana Vazquez*, Luis Morier*, Angel Alvarez*, Ernest A Gould‡, Maria G. Guzman* , and Scott B Halstead§
, Mayling Alvarez*, Rosmari Rodriguez-Roche*, Lídice Bernardo*, Tibaire Montes†, Susana Vazquez*, Luis Morier*, Angel Alvarez*, Ernest A Gould‡, Maria G. Guzman* , and Scott B Halstead§Table 2
Neutralization of dengue viruses by dengue virus 1–immune serum collected 4–8 years (group 1) and 20–22 years (group 2) after primary infection*
| Serotype (strain) | Group 1 | Group 2 | ||
|---|---|---|---|---|
| Positivity (%) | GMT | Positivity (%) | GMT | |
| DENV-1 (Jamaica/77) | 50 (100) | 93 | 89 (100) | 140.6 |
| DENV-2 (A15/81) | 6 (12) | 5.5 | 19 (21) | 6.5 |
| DENV-2 (I348600) | 36 (72)† | 30 | 40 (45)‡ | 10.2 |
| DENV-3 (116/00) | 4 (8) | 5.6 | 9 (10) | 5.9 |
| DENV-4 (Dominica) | 1 (2) | 5.1 | 13 (15) | 6.2 |
*GMT, geometric mean titer; DENV, dengue virus.
†p<0.00001 compared with DENV-2 (A15/81), DENV-3, and DENV-4 viruses in group 1.
‡p<0.01–0.0001 compared with DENV-2 (A15/81), DENV-3, and DENV-4 viruses in group 2.
