Volume 13, Number 2—February 2007
Research
Community-associated Methicillin-resistant Staphylococcus aureus Isolates and Healthcare-Associated Infections1
Cynthia L. Maree*, Robert S. Daum†, Susan Boyle-Vavra†, Kelli Matayoshi‡2, and Loren G. Miller*‡
Table 1
Patients with healthcare-associated MRSA isolates, 1999–2004, and predictors of SCCmec type IV phenotype*
| Characteristic | Patients with HA-MRSA Isolates, % (no.) | SCCmec phenotype,% (no.) | Predictors of SCCmec type IV phenotype | ||||
|---|---|---|---|---|---|---|---|
| Bivariate anaylsis | Multivariate analysis | ||||||
| Type IV | Type II/III | Odds ratio (95% CI) | p value | Odds ratio (95% CI) | p value | ||
| Total | (352) | 36 (128) | 64 (224) | ||||
| Sex | |||||||
| F | 35 (123) | 36 (44) | 64 (79) | 0.87 | >0.05 | ||
| M | 65 (229) | 37 (84) | 63 (145) | ||||
| Age, y | |||||||
| Mean | 50 ± 19 SD | 47±1.7 SE | 51±1.3 SE | 0.02 | >0.05 | ||
| Median (range) | 50 (<1–97) | 48 (<1–87) | 54 (<1–97) | ||||
| Time from admission to specimen collection, d | |||||||
| Mean | 19 ± 21 SD | 15±1.9 SE | 21±1.4 SE | 0.01 | 0.88 (0.8–0.98)† | 0.02 | |
| Median (range) | 12 (4–184) | 8 (4–174) | 15 (4–184) | ||||
| Culture specimen source | |||||||
| Blood | 10 (35) | 46 (16) | 54 (19) | 2.6 (1.2–5.7) | 0.02 | 2.2 (0.97–5.0) | 0.058 |
| Sputum | 34 (188) | 25 (29) | 75 (89) | Reference | Reference | ||
| Wound | 38 (133) | 49 (65) | 51 (68) | 2.9 (1.7–5.0) | <0.0001 | 2.6 (1.5–4.6) | 0.001 |
| Other | 19 (66) | 27 (18) | 73 (48) | 1.2 (0.6–2.3) | 0.69 | 1.1 (0.5–2.2) | 0.82 |
| Year culture specimen collected | |||||||
| 1999 | 52 (15) | 17 (9) | 83 (43) | Reference | <0.0001‡ | Reference | <0.0001 |
| 2000 | 57 (16) | 19 (11) | 81 (46) | 1.1 (0.4–3.0) | NS§ | ||
| 2001 | 65 (19) | 28 (18) | 72 (47) | 1.8 (0.7–4.5) | 1.8 (0.9–3.7) | ||
| 2002 | 47 (13) | 43 (20) | 57 (27) | 3.5 (1.4–8.9] | 3.2 (1.5–6.9) | ||
| 2003 | 63 (18) | 56 (35) | 44 (28) | 6.0 (2.4–14.3) | 5.2 (2.5–10.5) | ||
| 2004 | 68 (19) | 52 (35) | 48(33) | 5.1 (2.1–12) | 4.4 (2.2–8.8) | ||
*MRSA, methicillin-resistant Staphylococcus aureus; HA, healthcare associated; CI, confidence interval; SD, standard deviation; SE, standard error; NS, not significant; boldface indicates significance.
†Multivariate analysis results reflect time in weeks.
‡Measured with the Cochran-Armitage test of trends.
§Was not a significant predictor in the multivariate model.
