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Volume 13, Number 2—February 2007

Letter

African Tickbite Fever in Travelers, Swaziland

Paul M. Oostvogel*Comments to Author , Gerard J. van Doornum†, Russouw Ferreira‡, Jacqueline Vink*, Florence Fenollar§, and Didier Raoult§
Author affiliations: *Medical Center Haaglanden, The Hague, the Netherlands; †Erasmus University Hospital, Rotterdam, the Netherlands; ‡Skukuza, Republic of South Africa; §Université de la Mediterranée, Marseille, France;

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Table

Clinical and serologic characteristics of 12 travelers with African tickbite fever, Swaziland, 2003*

TSex/
age, yFever/headache/
myalgia/rashTickbite/
eschar site/
lymph. siteSeraRotterdam, the NetherlandsMarseille, France
Rickettsia conorii IgG/IgM†R. rickettsii IgG/IgM†R. conorii IgG/IgM†R. africae IgG/IgM†WBWB ads.
1F/47Y/N/Y/YN/N/groinA0/3232/320/00/0NTNT
C>128/>128>128/32128/0128/0+Ra
2M/14Y/Y/N/NY/foot/groinA>64/>64>64/>6432/064/0+Ra
C>128/32>128/16256/0256/0NTNT
3M/13N/N/N/NN/N/NA0/032/00/160/16+NC
C0/00/00/160/16NTNT
4M/10N/N/N/NN/N/groinA>64/>64>64/>640/160/32+Ra
C>128/32>128/160/640/64NTNT
5M/50Y/Y/N/YN/N/groinA0/00/00/00/0NTNT
C>128/>128>128/3264/864/8+NC
6M/13N/N/N/NN/N/groinA0/00/00/00/0NTNT
C>128/16>128/1632/1632/16+Ra
7M/11Y/N/N/NN/N/retro.A0/032/00/00/0NTNT
C0/>12816/320/320/32+NC
8F/47Y/Y/Y/YN/mult./groinA0/032/00/160/16+NC
C>128/16>128/032/832/8NTNT
9M/5Y/N/N/NY/thumb/
axillaryCNT/NTNT/NT0/00/0RaNT
10M/44Y/Y/Y/NN/shoulder/
axillaryC32/32>128/>1280/00/0+Ra
11F/10N/N/N/NN/N/trunkC0/00/00/00/0+Ra
12M/50N/N/N/NN/N/NC0/00/00/80/16+Ra

*T, traveler; lymph., lymphadenopathy; IgG, immunoglobulin G; WB = Western blot; WB ads., WB after cross-adsorption that removed antibodies to R. conorii; Y, yes; N, no; A, acute phase; NT, not tested; C, convalescent phase; +, positive for R. africae and R. conorii; Ra, positive for R. africae; NC, not conclusive; retro., retroauricular; mult., multiple.
†Ratio of titers.

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