Volume 13, Number 3—March 2007
Research
Effectiveness of Neuraminidase Inhibitors for Preventing Staff Absenteeism during Pandemic Influenza
Vernon J. Lee*
and Mark I. Chen*
and Mark I. Chen*Table 2
Effects of influenza pandemic prevention strategies on healthcare worker absenteeism
| Reproductive no. (R0) | Pandemic duration, wk | Peak % absent by strategy (days with >5% absent) | ||||||
|---|---|---|---|---|---|---|---|---|
| No action | Treatment only | 2 weeks’ prophylaxis | 4 weeks’ prophylaxis | 6 weeks’ prophylaxis | 8 weeks’ prophylaxis | |||
| 1.5 | 24 | 2.8 (0) | 2.1 (0) | 2.1 (0) | 2.1 (0) | 2.2 (0) | 2.3 (0) | |
| 2 | 15 | 6.7 (17.8) | 5.1 (5.4) | 5.2 (6.5) | 5.5 (9.1) | 5.9 (11)) | 4.6 (0) | |
| 2.5 | 12 | 10.2 (21.1) | 7.9 (16) | 8.1 (16.2) | 8.8 (16.2) | 7.2 (10.8) | 2 (0) | |
| 3 | 10 | 13 (20.6) | 10.2 (16.6) | 10.6 (16.7) | 11.4 (15) | 4.7 (0) | 2.5 (0) | |
| 4 | 8 | 17.3 (18.7) | 13.9 (15.7) | 14.6 (15.4) | 10.8 (11.1) | 3.7 (0) | 3.7 (0) | |
| 6 | 6 | 22.5 (16.5) | 18.5 (13.9) | 19.7 (12.9) | 5.5 (4.1) | 5.5 (4.1) | 5.5 (4.1) | |
| Pandemic similar to 1918 “Spanish flu”* | 20.2 (28.6) | 15.1 (18.3) | 15.8 (17.9) | 11.6 (13) | 4.1 (0) | 4.1 (0) | ||
*R0 =4; mortality rate = 5% (hospitalization set to the ratio of the hospitalization rates to the case-fatality rates in Table 1).
