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Volume 13, Number 4—April 2007

Research

Diagnosis of Tuberculosis by an Enzyme-Linked Immunospot Assay for Interferon-γ

Jann-Yuan Wang, Chien-Hong Chou, Li-Na Lee, Hsiao-Leng Hsu, I-Shiow Jan, Po-Ren HsuehComments to Author , Chuan-Liang Kao, and Kwen-Tay Luh

Author affiliations: *National Taiwan University Hospital, Taipei, Taiwan, Republic of China;

Main Article

Table 1

Clinical characteristics of 65 patients suspected of having tuberculosis, Taiwan, 2005*

Characteristic Value
Mean age, y (range) 52.2 (2–84)
Male:female (% male) 37:28 (56.9)
Underlying medical condition 35 (53.8)
Malignancy 17 (26.2)
Diabetes mellitus 12 (18.5)
Other† 11 (16.9)
Symptoms‡
  Cough or dyspnea [no. with hemoptysis] 44 (67.7) [2]
  Fever 35 (53.8)
  Mean duration of symptoms (range) 23.4 wk (2 wk– 5 y)
Radiographic finding
  Upper lobe fibroexudative lesions [no. with cavitation] 25 (38.5) [2]
  Multiple patches of alveolar infiltrates [no. with cavitation] 20 (30.8) [1]
  Multiple nodules or mass [no. with cavitation] 10 (15.4) [3]
  Upper lobe fibrotic change 5 (7.7)
  Pleural effusion [no. with upper lobe fibrotic change] 3 (4.6) [1]
  Miliary lesion 2 (3.1)
Acid-fast smear positive 33 (50.8)
Mycobacterial culture 48 (73.8)
  Mycobacterium tuberculosis 37 (56.9)
  M. avium-intracellulare complex 2 (3.1)
  M. chelonae 2 (3.1)
  M. abscessus and M. chelonae 2 (3.1)
  M. abscessus 1 (1.5)
  M. marinum 1 (1.5)
  M. kansasii 1 (1.5)
  Unidentified species 2 (3.1)

*Values are no. (%) unless otherwise indicated.
†Underlying disease was alcoholism in 4 patients, AIDS in 3 patients, end-stage renal disease in 2 patients, Sjogren syndrome in
1 patient, and hepatitis B-related liver cirrhosis in 1 patient.
‡Two patients were asymptomatic and had abnormal chest radiographs noted incidentally.

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