Volume 13, Number 6—June 2007
Strategies to Reduce Person-to-Person Transmission during Widespread Escherichia coli O157:H7 Outbreak
|Description||Model parameter||Values used for base analysis (range*)|
|Mean duration of incubation†||ζ||5 d (2–8 d)|
|Probability of symptomatic response||Psym||0.28|
|Mean duration of infection*||σ, δ||16 d (4–29 d)|
|Mean duration of protection from infection*||γ||56 d (35–77 d)|
|Hypergeometric dose response relation||α, β||0.08, 1.44|
|Nonoutbreak annual disease incidence in United States||73,480 cases|
|Population||N||275 million persons|
|Proportion of cases due to person-to-person transmission||k||0.12–0.75|
|Timing of interventions||0,1, and 2 weeks after press release|
|Effectiveness of Interventions||R(t)||1%–25%|
*Range used for uncertainty analysis.
†Inverse is used as a rate in the model (i.e., units of days–1).