Volume 13, Number 6—June 2007
Research
Strategies to Reduce Person-to-Person Transmission during Widespread Escherichia coli O157:H7 Outbreak
Edmund Y.W. Seto*, Jeffrey A. Soller†
, and John M. Colford*
, and John M. Colford*Table
Disease transmission model parameter values
| Description | Model parameter | Values used for base analysis (range*) |
|---|---|---|
| Mean duration of incubation† | ζ | 5 d (2–8 d) |
| Probability of symptomatic response | Psym | 0.28 |
| Mean duration of infection* | σ, δ | 16 d (4–29 d) |
| Mean duration of protection from infection* | γ | 56 d (35–77 d) |
| Hypergeometric dose response relation | α, β | 0.08, 1.44 |
| Nonoutbreak annual disease incidence in United States | 73,480 cases | |
| Population | N | 275 million persons |
| Proportion of cases due to person-to-person transmission | k | 0.12–0.75 |
| Timing of interventions | 0,1, and 2 weeks after press release | |
| Effectiveness of Interventions | R(t) | 1%–25% |
*Range used for uncertainty analysis.
†Inverse is used as a rate in the model (i.e., units of days–1).
