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Volume 13, Number 8—August 2007

Dispatch

Possible Autochthonous Malaria from Marseille to Minneapolis

Barbara Doudier*†, Hervé Bogreau†, Aaron DeVries‡, Nicolas Ponçon§, William M Stauffer‡, Didier Fontenille§, Christophe Rogier†, and Philippe Parola*†Comments to Author 
Author affiliations: *Hôpital Nord, Marseille, France; †Institut de Médecine Tropicale du Service de Santé des Armées, Marseille, France; ‡University of Minnesota, Minneapolis, Minnesota, USA; §Institut de Recherche pour le Développement, Montpellier, France;

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Table 2

Two strains of Plasmodium falciparum obtained from 2 patients with no recent travel history in malaria-endemic areas*

Dhfr
Dhps
Pfcrt
51 16 108 164 59 613 540 581 436 437 76
Autochthonous 1† GCA AAC ATA TGT GCC AAA GCG TCT GCT ACA
Autochthonous 2‡ ATT GCA AAC ATA CGT GCC AAA GCG TCT GGT AAA
3D7§ AAT GCA AGC ATA TGT GCC AAA GCG TCT GGT AAA
W2§ ATT GCA AAC ATA CGT TCC AAA GCG TTT GGT ACA

*Dhfr, dihydrofolate reductase gene; Dhps, dihydropteroate synthase; Pfcrt, P. falciparum chloroquine-resistance transporter. Underlines indicate positions that can be mutated.
†Patient 1, P. falciparum diagnosed in France.
‡Patient 2, P. falciparum diagnosed in the United States.
§Two parasite strains (3D7 and W2) were genotyped as a positive control; water was used as a negative control.

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