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Volume 14, Number 10—October 2008

Dispatch

Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia

Naman K. Shah, Alisa P. Alker, Rithy Sem, Agustina Ika Susanti, Sinuon Muth, Jason D. Maguire, Socheat Duong, Frederic Ariey, Steven R Meshnick, and Chansuda WongsrichanalaiComments to Author 
Author affiliations: University of North Carolina School of Public Health, Chapel Hill, North Carolina, USA (N.K. Shah, A.P. Alker, S.R. Meshnick); National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia (R. Sem, S. Muth, S. Duong); Pasteur Institute of Cambodia, Phnom Penh, (R. Sem, F. Ariey); US Naval Medical Research Unit No. 2, Jakarta, Indonesia (A.I. Susanti, J.D. Maguire, C. Wongsrichanalai);

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Table 1

Clinical characteristics of study participants at 5 surveillance sites, Cambodia, May 2004–December 2006*

Characteristic Pailin Kg. Seila† Chumkiri Memut Rattanakiri
Total no. 146 11 116 172 299
Male, no. (%) 98 (67.1) 9 (81.8) 97 (83.6) 62 (36.1) 187 (62.5)
Adult (>18 y), no. (%) 128 (87.7) 11 (100.0) 109 (94.0) 172 (100.0) 221 (73.9)
Parasitemia,‡ geometric mean 15,001 5,975 13,503 19,800 22,443
Parasitemia >50,000, no. (%) 47 (32.2) 4 (36.4) 33 (28.7) 68 (39.8) 120 (40.4)
Gametocytemia, no. (%) 8 (5.5) 1 (9.0) 11 (9.6) 12 (7.0) 8 (2.7)
Smear-positive malaria in past y, no. (%) 35 (39.3) 2 (20.0) 25 (61.0) 13 (7.6) 127 (46.7)
Antimalarial drug taken in past mo, no. (%) 13 (14.4) 2 (18.2) 20 (17.2) 64 (37.2) 6 (2.0)
Mixed infection, no. (%) 6 (4.1) 1 (9.1) 8 (7.0) 3 (1.8) 6 (2.0)
No. d of illness, median (range) 3 (1–6) 4 (2–6) 6 (1–6) 4 (2–6) 4 (0–6)

*The missing values by category include parasitemia (n = 4), gametocytemia (n = 4), smear-positive malaria in past year (n = 160), antimalarial drug taken in past month (n = 56), mixed infection (n = 4), and no. of d of illness (n = 21).
†Baseline differences were most likely due to small sample size.
‡Parasites/μL.

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