Skip directly to search Skip directly to A to Z list Skip directly to site content
CDC Home

Volume 14, Number 2—February 2008

Dispatch

Prolonged Plasmodium falciparum Infection in Immigrants, Paris

Eric D’Ortenzio*1Comments to Author , Nadine Godineau†, Arnaud Fontanet‡, Sandrine Houze*, Olivier Bouchaud¶#, Sophie Matheron***, and Jacques Le Bras*
Author affiliations: *Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris, France; †Centre Hospitalier Général Delafontaine, Saint-Denis, France; ‡Institut Pasteur, Paris, France; §Université Paris Descartes, Paris, France; ¶Centre Hospitalier Universitaire Avicenne, Bobigny, France; #Université Paris 13, Paris, France; **Université Paris Diderot, Paris, France;

Main Article

Table 1

Univariate analysis of factors associated with prolonged Plasmodium falciparum infection in 248 immigrant travelers*

Variable Case-patients (n = 61), no. (%) Controls (n = 197), no. (%) OR (95% CI) p value
Sex
Female 33 (54.1) 75 (38.1) 1
Male
28 (45.9)
122 (61.9)
0.52 (0.29–0.93)
0.03
Age, y
<5 2 (3.3) 10 (5.1) 1
5–14 5 (8.2) 18 (9.1) 1.39 (0.22–8.51)
15–60 53 (86.9) 163 (82.7) 1.63 (0.34–7.66) 0.83
>60
1 (1.6)
6 (3.1)
0.83 (0.06–11.23)

Origin
Sub-Saharan Africa 55 (90.2) 181 (91.9) 1
Comoros Islands 5 (8.2) 14 (7.1) 1.18 (0.41–3.41)
Other 1 (1.6) 2 (1) 1.65 (0.15–18.5) 0.89
South America 0 1 (0.5) NA
Caribbean 0 1 (0.5) NA
India
1 (1.6)
0
NA

First-arrival immigrant
No 24 (39.3) 183 (92.9) 1
Yes
37 (60.7)
14 (7.1)
20.15 (9.54–42.57)
<0.001
Region of malaria acquisition
West Africa 32 (52.5) 132 (67) 1
Central Africa 22 (36.1) 44 (22.3) 2.06 (1.09–3.92) 0.03
East Africa 1 (1.6) 2 (1) 2.06 (0.18–23.46)
Comoros Islands 5 (8.2) 18 (9.1) 1.15 (0.4–3.32)
Other
1 (1.6)
1 (0.5)
4.12 (0.25–67.74)

Chemoprophylaxis
No 50 (82) 118 (59.9) 1
Yes 9 (14.8) 71 (36) 0.3 (0.14–0.65) 0.002
Unknown
2 (3.2)
8 (4.1)
NA

Prophylaxis with mefloquine
No 56 (91.8) 186 (94.4) 1
Yes 3 (4.9) 3 (1.5) 3.32 (0.65–16.92) 0.15
Unknown
2 (3.3)
8 (4.1)
NA

Antimalarial self-medication
No 55 (90.2) 171 (86.8) 1
Yes 5 (8.2) 15 (7.6) 1.04 (0.36–2.98) 0.95
Unknown 1 (1.6) 11 (5.6) NA
Men 28 (45.9) 122 (61.9) 1
Nonpregnant women 16 (26.2) 69 (35) 1.01 (0.51–2)
Pregnant women
17 (27.9)
6 (3.1)
12.35 (4.46–34.14)
<0.001
HIV status
Negative 22 (36.1) 42 (21.3) 1
Positive 12 (19.7) 6 (3.1) 3.82 (1.26–11.56) 0.02
Unknown
27 (44.3)
149 (75.6)
NA

Symptomatic malaria
No 8 (13.1) 0 (0) 1
Yes
53 (86.9)
197 (100)
0.3 (0.25–0.47)
<0.001
Parasitemia†
High 2 (3.3) 18 (9.1) 1
Low 59 (96.7) 179 (90.9) 1.61 (0.53–4.9) 0.4

*OR, odds ratio; CI, confidence interval; NA, not applicable.
†Parasitemia (parasitized erythrocytes) was considered high if >4% and low if <4% by World Health Organization criteria.

Main Article

1Current affiliation: Institut de Veille Sanitaire, Saint-Denis, Réunion Island, France

Top of Page

USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO