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Volume 14, Number 2—February 2008

Research

Streptococcus pneumoniae Serotype 19A in Children, South Korea

Eun Hwa Choi*†, So Hee Kim*, Byung Wook Eun*, Sun Jung Kim†, Nam Hee Kim‡, Hoan Jong Lee*¶Comments to Author , and Jina Lee§Comments to Author 
Author affiliations: *Seoul National University College of Medicine, Seoul, South Korea; †Seoul National University Bundang Hospital, Seongnam, South Korea; ‡Inje University College of Medicine, Goyang, South Korea; §Seoul National University Boramae Hospital, Seoul, South Korea; ¶Seoul National University Hospital, Seoul, South Korea;

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Table 2

Antimicrobial susceptibility and mef and erm prevalence of serogroup 19 pneumococcal isolates from children in South Korea, 1991–2006, according to sequence type

CC or ST* (no. strains) Serotypes Multidrug resistance† MIC50 (range) in µg/mL for each antimicrobial drug
mef/erm determinants
Penicillin Cefotaxime Erythromycin
CC271-related‡ (116) 19A, 19F Yes 1.5 (1.0–3.0) 1.0 (0.75–4.0) >256 (>256) mef+, erm+
ST1203 (1) 19F No 0.5 0.25 0.5 mef
ST1374 (4) 19A Yes 0.06 (0.04–0.06) 0.12 (0.09–0.12) >256 (>256) mef
ST2394 (1) 19A Yes 1.0 0.5 2.0 mef+, erm
ST2395 (3) 19F Yes 4.0 (4.0) 2.0 (1.0–2.0) 2.0 (2.0) mef+, erm
ST2399 (1) 19F Yes 0.12 0.25 8.0 mef+, erm

*CC, clonal complex; ST, sequence type.
†Resistant to at least 3 antimicrobial drug classes.
‡CC271-related sequence types: ST320 (59 isolates), ST271 (14), ST236 (14), ST283 (7), ST1451 (1), ST1464 (10), ST2395 (3), ST2695 (3), and 1 isolate of each of ST1412, ST1417, ST2396, ST2397, ST2398, ST2694, ST2696, ST2697, and ST2698.

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