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Volume 14, Number 4—April 2008

Dispatch

Neuroinvasion by Mycoplasma pneumoniae in Acute Disseminated Encephalomyelitis

Bernhard Stamm*Comments to Author , Michael Moschopulos*, Hansjoerg Hungerbuehler*, Jeannette Guarner†, Gillian L. Genrich†, and Sherif R. Zaki†
Author affiliations: *Kantonsspital Aarau, Aarau, Switzerland; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA;

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Figure

A) Subcortical cerebral white matter with numerous perivascular foci of demyelination and necrosis (hematoxylin and eosin stain, original magnification ×40). B) Immunohistochemical evidence of Mycoplasma pneumoniae antigen inside macrophages present in the perivascular inflammatory infiltrate (immunohistochemical assay performed by using the monoclonal anti–M. pneumoniae antibody and naphthol fast red as counterstain, original magnification ×100).

Figure. A) Subcortical cerebral white matter with numerous perivascular foci of demyelination and necrosis (hematoxylin and eosin stain, original magnification ×40). B) Immunohistochemical evidence of Mycoplasma pneumoniae antigen inside macrophages present in the perivascular inflammatory infiltrate (immunohistochemical assay performed by using the monoclonal anti–M. pneumoniae antibody and naphthol fast red as counterstain, original magnification ×100).

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