Volume 14, Number 4—April 2008
Research
Emericella quadrilineata as Cause of Invasive Aspergillosis
Paul E. Verweij*
, János Varga†‡, Jos Houbraken†, Antonius J.M.M. Rijs*, Frans M. VerduynLunel*, Nicole M.A. Blijlevens*, Yvonne R. Shea§, Steven M. Holland§, Adilia Warris*, Willem J. G. Melchers*, and Robert A. Samson†
, János Varga†‡, Jos Houbraken†, Antonius J.M.M. Rijs*, Frans M. VerduynLunel*, Nicole M.A. Blijlevens*, Yvonne R. Shea§, Steven M. Holland§, Adilia Warris*, Willem J. G. Melchers*, and Robert A. Samson†Table
Antifungal activities against Emericella nidulans and E. quadrilineata
| Drug | MIC, mean |
Significance* | |
|---|---|---|---|
| E. nidulans (n = 12) | E. quadrilineata (n = 12) | ||
| Amphotericin B | 2.5 | 0.5 | p<0.05 |
| Itraconazole | 0.07 | 0.13 | NS |
| Voriconazole | 0.26 | 0.39 | p<0.05 |
| Posaconazole | 0.25 | 0.22 | p<0.05 |
| Caspofungin† | 0.32 | 1.83 | p<0.05 |
| Terbinafine | 0.01 | 0.009 | NS |
*NS, not significant.
†Mean minimum effective concentration was compared.
