Volume 14, Number 6—June 2008
Letter
Inquilinus limosus and Cystic Fibrosis
Fadi Bittar*, Anne Leydier†, Emmanuelle Bosdure†, Alexandre Toro*, Martine Reynaud-Gaubert‡, Stéphanie Boniface‡, Nathalie Stremler†, Jean-Christophe Dubus†, Jacques Sarles†, Didier Raoult*, and Jean-Marc Rolain*
Table
Clinical and epidemiologic features of cystic fibrosis (CF) patients with Inquilinus limosus*
| Case no. | Age, y/sex | Lung transplant | Positive samples | Clinical manifestation (first isolation) | Growth on MacConkey agar | Growth on selective agar (d) | Phenotypic identification† | Other associated pathogens | Reference |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 22/F | Yes | Lung explant, BAL, sputum | Pneumonia | Poor | ND | AR | PA, PM | (1) |
| 2 | 17/M | No | Sputum | Stable | No | Yes (6 d) | SP | SA, PA, CA | (3) |
| 3 | 14/F | No | Sputum | Stable | No | Yes (5 d) | SP | PA, AF, CA | (3) |
| 4 | 12/M | No | Sputum | Stable | ND | Yes (ND) | SP | PA, SM, SA, AX | (5) |
| 5 | 13/F | No | Sputum | Exacerbation | ND | Yes (ND) | SP | PA, SA, AF | (5) |
| 6 | 8/M | No | Sputum | Stable | ND | Yes (ND) | SP | PA | (5) |
| 7 | 10/M | No | Sputum | Stable | ND | Yes (ND) | SP | None | (5) |
| 8 | 18/M | No | Sputum | Exacerbation | ND | Yes (ND) | AR | PA, SA, AF | (5) |
| 9 | 16/F | No | Sputum | Severe exacerbation | ND | ND | PA | PA | (4) |
| 10 | 19/M | No | Sputum | Stable | ND | ND | ND | PA | (4) |
| 11 | 17/F | No | Sputum | Exacerbation | ND | ND | ND | PA, CA, AF | (4) |
| 12 | 20/F | No | Sputum | Exacerbation | ND | ND | ND | PA, SA, CA, AF | (4) |
| 13 | 17/F | No | Sputum | Stable | ND | ND | ND | PA, SA, SM, CA, AF | (4) |
| 14 | 35/M | No | Sputum | Respiratory decline | ND | ND | PA | PA, SM, SMA | (4) |
| 15 | 17/F | No | Sputum | Stable | No | Yes (4 d) | SP | CA | This study |
| 16 | 2/M | No | Sputum | Productive cough | No | Yes (3 d) | SP | SA, HI | This study |
| 17 | 21/M | No | Sputum | Exacerbation | No | Yes (3 d) | AR | PA, AF | This study |
| 18 | 15/M | No | Sputum | Fever and thoracic pain | No | Yes (3 d) | AR | SA | This study |
*BAL, bronchoalveolar lavage; ND, not determined; AR, Agrobacterium radiobacter; PA, Pseudomonas aeruginosa; PM, Proteus mirabilis; SP, Sphingomonas paucimobilis; SA, Staphylococcus aureus; CA, Candida albicans; AF, Aspergillus fumigatus; SM, Stenotrophomonas maltophilia; AX, Achromobacter xylosoxidans; SMA, Serratia marcescens; HI, Haemophilus influenzae.
†Phenotypic identification was obtained by using the BIOLOG GN MicroPlate assay (BIOLOG Inc., Hayward, CA, USA) for case 1 and the API 20NE kit system (bioMérieux, Marcy l’Etoile, France) for cases 2–8 and 15–18.
