Emerging Infectious Disease ISSN: 1080-6059

Determinants of Cluster Size in Large, Population-Based Molecular Epidemiology Study of Tuberculosis, Northern Malawi

Judith R. Glynn*

, Amelia C. Crampin*†, Hamidou Traore*, Steve Chaguluka†, Donex T. Mwafulirwa†, Saad Alghamdi*, Bagrey M.M. Ngwira†, Malcolm D. Yates‡, Francis D. Drobniewski‡, and Paul E.M. Fine*

Author affiliations: *London School of Hygiene and Tropical Medicine, London, UK; †Karonga Prevention Study, Chilumba, Malawi; ‡Health Protection Agency, London;

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Figure

Geographic distribution of the 4 most common strains defined by restriction fragment length polymorphism: A) strain kps12, B) strain kps121, C) strain kps41, and D) strain kps44. Each o represents a patient. Each square is 10 km × 10 km. The background shading represents the total number of tuberculosis (TB) cases in each area during the study period, which largely reflects the population density.

Figure. Geographic distribution of the 4 most common strains defined by restriction fragment length polymorphism: A) strain kps12, B) strain kps121, C) strain kps41, and D) strain kps44. Each o represents a patient. Each square is 10 km × 10 km. The background shading represents the total number of tuberculosis (TB) cases in each area during the study period, which largely reflects the population density.

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