Volume 14, Number 7—July 2008
CME ACTIVITY
Alcaligenes xylosoxidans Bloodstream Infections in Outpatient Oncology Office
Table
Characteristics of 12 case-patients with bacteremia caused by Alcaligenes xylosoxidans*
| Case-patient no. | Age, y | Sex | Underlying disease | Date of CVC flush | Date of onset, symptoms† | Date of blood collection‡ |
|---|---|---|---|---|---|---|
| Case–control study | ||||||
| 1 | 70 | F | Acute myelogenous leukemia | 2001 Nov 19 | 2001 Nov 19, rigors after flush | 2001 Nov 19 |
| 2 | 65 | F | Breast cancer | 2001 Dec 5 | 2001 Dec 5, no chart record of symptoms after flush, blood culture obtained next day | 2001 Dec 6 |
| 3 | 73 | F | Colon cancer | 2001 Dec 7 | 2001 Dec 7, fever after flush | 2001 Dec 7 |
| 4 | 41 | F | Sickle cell disease | 2001 Dec 4 | 2001 Dec 11, myalgias, emesis | 2001 Dec 11 |
| 5 | 73 | F | Gastric cancer | Unknown | Unknown | 2001 Dec 13 |
| 6 | 71 | M | Colon cancer | 2001 Dec18 | 2001 Dec 19, fever, chills | 2001 Dec 20 |
| 7 | 79 | F | Pancreatic cancer | Unknown | Unknown | 2001 Dec 30 |
| 8 | 45 | F | Breast cancer | 2002 Jan 10 | 2002 Jan 10, no chart record of symptoms after flush, blood culture obtained next day | 2001 Jan 10 |
| 9 |
70 |
F |
Non-Hodgkin lymphoma |
2002 Jan 10 |
2002 Jan 10, hypotension after infusion |
2002 Jan 11 |
| Prospective study | ||||||
| 10 | 77 | F | Squamous cell cancer of palate | NA | 2001 Nov/Dec, intermittent nausea and weakness | 2002 Jan 29 |
| 11 | 77 | M | Gastric cancer | NA | 2001 Nov/Dec, intermittent fever, chills after flushes, not reported to Office B staff | 2002 Feb 7 |
| 12 | 49 | F | Non-Hodgkin lymphoma | NA | Asymptomatic | 2002 Feb 5 |
*CVC, central venous catheter; NA, not applicable.
†Signs and symptoms of bloodstream infection.
‡Collection of blood that had subsequent positive culture result for A. xylosoxidans.


