Volume 14, Number 9—September 2008
Research
Pediatric Parapneumonic Empyema, Spain
, Carmen Muñoz-Almagro, Luis A. Arroyo, David Tarrago, David Sanchez-Tatay, David Moreno-Perez, Sahar S. Dhillon, Cristina Esteva, Susanna Hernandez-Bou, Juan J. Garcia-Garcia, William P. Hausdorff, and Angela B. BrueggemannTable 5
Characteristics of children hospitalized with PPE, by serotype category, excluding patients with serious underlying disease (n = 3)*
| Characteristic | HIDP serotypes, n = 84 | Serotype 3, n = 11 | LIDP serotypes, n = 13 | p value |
|---|---|---|---|---|
| Median age, mo (range) | 55.6 (2–180) | 37.9 (9–71) | 24 (2–36) | 0.0001† |
| Median hospital stay,‡ d (range) | 13 (4–38) | 15 (9–29) | 10 (6–24) | 0.042§ |
| Complications, % patients¶ | 10 | 45 | 0 | 0.004# |
*PPE, pediatric parapneumic empyema; HIDP, high invasive disease potential; LIDP, low invasive disease potential. HIDP serotypes: 1, 5, 7F, and 14; LIDP serotypes: 6A, 9V, 19A, and 19F (16,17,19). All results shown were statistically significant (p<0.05). There were no significant differences between groups for the following variables: median days febrile preadmission; preadmission antimicrobial therapy; intensive care unit admission; mean leukocyte count; mean C-reactive protein; mean pleural fluid glucose; mean pleural fluid pH; mean lactate dehydrogenase; median days to thorachocentesis; referral; primary fibrinolytics or thoracoscopy; or oxygen requirement >4 d.
†HIDP was compared with LIDP by post hoc analysis.
‡Since being admitted to first center.
§No significant differences between individual groups by post hoc analysis (p = 0.023 for comparison between serotype 3 and LIDP)
¶Complications included (no. patients): bronchopleural fistula (3), pyopneumothorax (2), pneumatoceles (4), lung abscess (1), mechanical ventilation
>48 h (2), severe anemia requiring blood transfusion (2), severe hypoalbuminemia requiring seroalbumin replacement (1).
#Serotype 3 compared with HIDP and LIDP groups combined.
