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Volume 14, Number 9—September 2008

Letter

Merkel Cell Polyomavirus and Merkel Cell Carcinoma, France

Vincent FoulongneComments to Author , Nicolas Kluger, Olivier Dereure, Natalie Brieu, Bernard Guillot, and Michel Segondy
Author affiliations: University of Montpellier I, Montpellier, France;

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Table

Merkel cell polyomavirus from 9 patients with Merkel cell carcinoma and 15 control patients, France*

Patient no. Age, y Sex Diagnosis Sample PCR primer pair
LT1 LT3 VP1
1 57 M MCC, primary Fresh biopsy, buttock + + +
2 61 F MCC, primary FFPE biopsy, buttock +
3 57 F MCC, primary FFPE biopsy, lower eyelid + +
4 82 F MCC, primary FFPE biopsy, cheek +
5 78 M MCC, metastatic Fresh biopsy, jugular lymph node + +
6 80 F MCC, primary Fresh biopsy, upper eyelid + +
7 65 M MCC, primary FFPE biopsy, temple +
8 81 M MCC, primary FFPE biopsy, forearm
9 60 M MCC, primary FFPE biopsy, forearm + +
10 61 M Hyperkeratosis Fresh biopsy, foot
11 49 M Seborrheic keratosis, penis Fresh biopsy, penis shaft
12 60 M Nonspecific lesion, esophagus Fresh biopsy, lesion
13 40 M Nasal papilloma Fresh biopsy, papilloma
14 58 M Anal condylomas Fresh biopsy, condyloma
15 44 M Epidermodysplasia verruciformis Fresh biopsy, skin
16 19 M Cutaneous warts Fresh biopsy, wart
17 57 F Cutaneous warts Fresh biopsy, wart
18 64 F Cutaneous nodule Fresh biopsy, skin
19 6 F Pharyngeal papillomatosis Fresh biopsy, pharynx
20 27 M Vocal cord polyp Fresh biopsy, polyp
21 58 M Lichen Fresh biopsy, skin
22 63 M Skin inflammation Fresh biopsy, skin
23 72 M Skin inflammation Fresh biopsy, skin
24 57 M Skin inflammation Fresh biopsy, skin

*MCC, Merkel cell carcinoma; +, positive Merkel cell polyomavirus PCR amplification; FFPE, formaldehyde-fixed paraffin-embedded; –, negative Merkel cell polyomavirus PCR amplification.

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