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Volume 15, Number 10—October 2009

Research

Mycobacterium tuberculosis Genotype and Case Notification Rates, Rural Vietnam, 2003–2006

Tran N. Buu, Mai N.T. Huyen, Nguyen N.T. Lan, Hoang T. Quy, Nguyen V. Hen, Matteo Zignol, Martien W. Borgdorff, Dick van Soolingen, and Frank G.J. CobelensComments to Author 
Author affiliations: Pham Ngoc Thach Tuberculosis and Lung Disease Hospital, Ho Chi Minh City, Vietnam (T.N. Buu, M.N.T. Huyen, N.T.N. Lan, H.T. Quy); Tien Giang Provincial Tuberculosis and Lung Disease Hospital, My Tho, Vietnam (N.V. Hen); World Health Organization, Geneva, Switzerland (M. Zignol); KNCV Tuberculosis Foundation, The Hague, the Netherlands (M.W. Borgdorff, F.G.J. Cobelens); Academic Medical Centre, Amsterdam, the Netherlands (M.W. Borgdorff, F.G.J. Cobelens); National Institute of Public Health and the Environment, Bilthoven, the Netherlands (D. van Soolingen)

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Table 2

Annual change in tuberculosis case notification rates, by genotype, Vietnam, 2003–2006*

Age group, y Absolute change in case rates Proportion of change caused by
p value
Beijing genotype infections Vietnam genotype infections Other genotype infections Within age groups
Among age groups
Beijing genotype† Vietnam genotype‡ Beijing 
genotype§
All 8.0 0.45 0.44 0.11 <0.001 <0.001
15–24 4.3 0.85 0.03 0.12 <0.001 <0.001 <0.001
25–64 8.0 0.53 0.47 0.00 0.818 0.907 0.818
>65 34.0 0.23 0.56 0.21 0.001 <0.05 0.001

*Per 100,000 population. Average weighted for difference in absolute changes.
†By χ2 test for comparison between Beijing and remaining genotypes in the same age group.
‡By χ2 test for comparison between Vietnam and remaining genotypes in the same age group.
§By χ2 test for comparison between each age group with the remaining age groups; Beijing vs. all remaining genotypes.

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