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Volume 15, Number 10—October 2009


Nontuberculous Mycobacteria Infections and Anti–Tumor Necrosis Factor-α Therapy

Kevin L. WinthropComments to Author , Eric Chang, Shellie Yamashita, Michael F. Iademarco, and Philip A. LoBue
Author affiliations: Oregon Health and Sciences University, Portland, Oregon, USA (K.L. Winthrop, E. Chang, S. Yamashita); US Public Health Service, Washington, DC, USA (M.F. Iademarco); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (P.A. LoBue)

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Table 2

Sites of infection for 105 reported anti–TNF-α therapy–associated cases of NTM disease, US Food and Drug Administration MedWatch database, 1999–2006*

Site No. (%) cases
Pulmonary region 59 (56)
Skin or soft tissue 27 (26)
Bone or joint 10 (9)
Disseminated 8 (8)
Eye 1 (1)

*TNF-α, tumor necrosis factor-α; NTM, nontuberculous mycobacteria.

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