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Volume 15, Number 10—October 2009

Research

Discriminatory Ability of Hypervariable Variable Number Tandem Repeat Loci in Population-based Analysis of Mycobacterium tuberculosis Strains, London, UK

Preya Velji1, Vladyslav Nikolayevskyy1, Timothy Brown, and Francis DrobniewskiComments to Author 
Author affiliations: Barts and The London School of Medicine, Queen Mary, University of London, London, UK (P. Velji, V. Nikolayevskyy); Health Protection Agency National Mycobacterium Reference Laboratory, London (T. Brown, F. Drobniewski); 1These authors contributed equally to this article.

Main Article

Table 1

Expected molecular weights of Mycobacterium tuberculosis of fragments at each locus, with different numbers of copies, London, UK, 2005–2006*

No. repeats Length of expected fragments for each locus, bp
MIRU 26 ETR-B VNTR 1982 VNTR 3232†
0 244 121 178
1 295 174 256 242
2 344 227 334 286
3 393 280 412 330
4 442 333 490 372
5 491 386 568 415
6 540 439 646 458
7 589 492 727 501
8 638 545 802 546
9 687 598 880 587
10 736 651 958 630
11 785 1,038 673
12 834 1,116 716
13 883 1,194 759
14 932 802
15 845
16 888
17 931
18 974
19 1,017
20 1,060

*MIRU, mycobacterial interspersed repetitive unit; ETR, exact tandem repeat; VNTR, variable number tandem repeats.
†No isolates had 0 repeats in locus 3232 in our population.

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