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Volume 15, Number 10—October 2009


Discriminatory Ability of Hypervariable Variable Number Tandem Repeat Loci in Population-based Analysis of Mycobacterium tuberculosis Strains, London, UK

Preya Velji1, Vladyslav Nikolayevskyy1, Timothy Brown, and Francis DrobniewskiComments to Author 
Author affiliations: Barts and The London School of Medicine, Queen Mary, University of London, London, UK (P. Velji, V. Nikolayevskyy); Health Protection Agency National Mycobacterium Reference Laboratory, London (T. Brown, F. Drobniewski); 1These authors contributed equally to this article.

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Table 4

Allelic variants of additional hypervariable VNTR loci that cannot be resolved with the CEQ automated sequencer*†

Locus Maximum no. repeats suitable for automated analysis Fragment size, bp Proportion of strains with allelic variants beyond the automated system resolution, %
3232 15 830 4.1
1982 9 880 11.9
2163A 11 876 10.8
3336 11 875 21.1

*Beckman Coulter, Fullerton, CA, USA.
†VNTR, variable number tandem repeats.

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