Hemorrhagic Fever with Renal Syndrome in 4 US Soldiers, South Korea, 2005
Jin-Won Song , Sung-Sil Moon1, Se Hun Gu, Ki-Joon Song, Luck Ju Baek, Heung Chul Kim, Todd Kijek2, Monica L. O’Guinn, John S. Lee, Michael J. Turell, and Terry A. Klein
Author affiliations: Korea University, Seoul, South Korea (J.-W. Song, S.-S. Moon, S.H. Gu, K.-J. Song, L.J. Baek); 65th Medical Brigade, Seoul (H.C. Kim, T. Kijek, T.A. Klein); US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA (M.L. O’Guinn, J.S. Lee, M.J. Turrell)
Figure 2. Phylogenetic tree by maximum parsimony method, rooted at the midpoint, based on the 320-bp region of G2 glycoprotein–encoding medium segment of 4 hemorrhagic fever with renal syndrome patients who were US soldiers in South Korea (patients 1–4), 2005 (GenBank accession nos. FJ561275–FJ561278) and field mice (Apodemus spp.)–borne Hantaan viruses (HTNV). HTNV sequence amplified from patient 1 was identical with a HTNV sequence (Aa04–1325) from A. agrarius mice captured at firing point (FP) 60. HTNV sequences from patients 2 and 4 were the same as 3 HTNV sequences (Aa05–1437, Aa06–119, Aa06–171) from A. agrarius mice captured at Twin Bridge Training Area–South (TBTA-S), and the HTNV sequence from patient 3 was identical to 11 HTNV sequences (Aa05–1465, Aa07–2, Aa07–21, Aa07–196, Aa07–206, Aa07–223, Aa07–280, Aa07–284, Aa07–288, Aa07–306 and Aa07–318) from A. agrarius mice at Twin Bridge Training Area-North (TBTA-N). Branch lengths are proportional to the number of nucleotide substitutions, while vertical distances are for clarity only. The numbers at each node are bootstrap probabilities (expressed as percentages), as determined for 100 iterations by using PAUP version 4.0b (http://paup.csit.fsu.poly). The colors indicate patients and corresponding training sites.
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