Volume 15, Number 2—February 2009
Systemic Infection with Enteric Adenovirus in Immunocompetent Child with Haemophilus influenzae Disease
|Dec 7||Patient hospitalized with 6-day history of fever >38°C and somnolence; blood culture positive for Hemophilus influenzae; isolate not typed (unavailable for further characterization)|
|Dec 9||CSF results: pleocytosis (2,710 leukocytes/mm3, 94% neutrophils); protein 178 mg/dL; glucose 11 mg/dL; CSF culture positive for H. influenzae; CSF Gram stain positive for gram-negative coccobacilli; antimicrobial drug treatment (ceftriaxone) started|
|Dec 11||New onset seizures, ataxia, and maculopapular rash on entire trunk and all extremities; no diarrhea or respiratory symptoms; brain ultrasound scan results within normal limits; anticonvulsant therapy (phenobarbital) started|
|Dec 12||CSF results: pleocytosis (100 leukocytes/mm3, 60% neutrophils, 40% monocytes); protein 131.6 mg/dL; glucose 31 mg/dL; CSF bacterial culture, results negative; CSF Gram stain results negative; patient enrolled in the encephalitis study; initial specimens for the study collected|
|Dec 22||Brain ultrasound scan results within normal limits; antimicrobial drug treatment (ceftriaxone) discontinued|
|Dec 23||CSF bacterial culture results negative; CSF Gram stain results negative; anticonvulsant therapy (phenobarbital) discontinued|
|Dec 27||Patient discharged in improved condition; discharge diagnosis: H. influenzae meningitis and septicemia|
|Jan 7†||Follow-up visit: full recovery without sequelae; convalescent-phase serum specimen obtained|
*CSF, cerebrospinal fluid.
1Current affiliation: University of Washington, Seattle, Washington, USA.
2Current affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.