Figure 1. Circular map of virulence plasmid pO113 generated by using circular_diagram.pl (Sanger Institute, Cambridge, UK) and Inkscape software (www.inkscape.org). The locations of proteins encoded on the leading and lagging strand are shown on the outer 2 rings. The colors indicate the assigned GenoList functional category (Institut Pasteur, Paris, France). The black ring indicates GC content, with high GC content outermost. The innermost ring shows GC skew.