Skip directly to search Skip directly to A to Z list Skip directly to site content
CDC Home

Volume 15, Number 4—April 2009

Research

Experimental Infection of Potential Reservoir Hosts with Venezuelan Equine Encephalitis Virus, Mexico

Eleanor R. Deardorff, Naomi L. Forrester, Amelia P. Travassos da Rosa, Jose G. Estrada-Franco, Roberto Navarro-Lopez, Robert B. Tesh, and Scott C. WeaverComments to Author 
Author affiliations: University of Texas Medical Branch, Galveston, Texas, USA (E.R. Deardorff, N.L. Forrester, A.P. Travassos da Rosa, J.G. Estrada-Franco, R.B. Tesh, S.C. Weaver); Comision Mexico–Estados Unidos para la Prevencion de la Fiebre Aftosa y Otras Enfermedades Exoticas de los Animales, Mexico City, Mexico (R. Navarro-Lopez)

Main Article

Table

Viremia in rodents that died 1–14 days after inoculation with 3.2 log10 PFU of Venezuelan equine encephalitis virus subtype IE strain MX01-22*

Rodent genus dpi† Tissue virus content (log10 PFU/g)†
Brain Heart Spleen Kidney Liver Lung
Oryzomys
2
1.8
2.7
3.3
2.0
3.2
0
Oligoryzomys 4 0 0 4.0 0 0 0

6
0
0
3.4
0
0
0
Baiomys 6 3.2 5.0 5.0 4.7 4.9 3.9
7 4.6 3.2 4.2 0 4.3 4.3
7 2.0 2.0 3.0 3.4 2.6 4.1
8 5.0 3.0 5.7 5.0 1.9 5.0

*Not shown are 3 Liomys salvini, 2 Oligoryzomys fulvescens, and 1 Sigmodon hispidus rodents. These animals died on days 5–10 postinoculation and showed no detectable virus in any organs tested. dpi, days postinoculation.
†Limit of detection was 1 plaque in150 μL homogenate. Tissue sample weight varied between 0.002 and 0.01 grams.

Main Article

Top of Page

USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO