Volume 15, Number 5—May 2009
Letter
Postoperative Panophthalmitis Caused by Whipple Disease
Michel Drancourt, Florence Fenollar, Danièle Denis, and Didier Raoult
Table
Characteristics of 19 patients with Whipple disease uveitis documented by presence of Tropheryma whipplei in a diseased eye*
| Patient. no. | Age, y/sex | Class | Location | Postoperative uveitis | Use of local or systemic steroids | Microscopy, PAS stain | EM | PCR | Reference |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 52/M | I | B | – | No | + | + | ND | (3) |
| 2 | 60/M | A | B | – | No | + | + | ND | (5) |
| 3 | 56/M | A | B | + | Yes | + | ND | ND | (4) |
| 4 | 47/M | A | B | – | Yes | + | ND | ND | (4) |
| 5 | 65/M | A | B | + | Yes | + | + | + | (6) |
| 6 | 59/F | A | B | + | Yes | + | + | + | (7)† |
| 7 | 53/F | Pa | U | – | Yes | + | ND | + | (7)† |
| 8 | 65/M | I | U | + | Yes | + | ND | + | (7)† |
| 9 | NR/NR | NR | NR | NR | NR | ND | ND | + | (8) |
| 10 | 65/M | I | U | + | Yes | ND | ND | +‡ | (7) |
| 11 | 81/M | P | U | + | Yes | ND | ND | +‡ | (7) |
| 12 | 35/M | P | U | NR | NR | ND | ND | +‡ | (7) |
| 13 | 46/M | P | U | – | No | ND | ND | +‡ | (7) |
| 14 | 3/F | A | U | – | No | ND | ND | +‡ | (7) |
| 15 | 90/F | A | U | + | Yes | ND | ND | +‡ | (7) |
| 16 | 69/M | P | U | + | Yes | ND | ND | +‡ | (7) |
| 17 | 20/F | A | U | + | Yes | ND | ND | +‡ | (7) |
| 18 | 74/F | Pa | U | + | Yes | ND | ND | +‡ | (7) |
| 19 | 78/F | P | U | + | Yes | ND | ND | +‡ | (7) |
*PAS, periodic acid–Schiff; EM, electron microscopy; I, intermediate; B, bilateral; ND, not done; A, anterior; Pa, panuveitis; U, unilateral; NR, not reported; P, posterior.
†Reviewed by Drancourt et al. (7).
‡These patients were considered to have suspected cases.
