Volume 15, Number 5—May 2009
Research
New Respiratory Enterovirus and Recombinant Rhinoviruses among Circulating Picornaviruses
Caroline Tapparel1
, Thomas Junier1, Daniel Gerlach, Sandra Van Belle, Lara Turin, Samuel Cordey, Kathrin Mühlemann, Nicolas Regamey, John-David Aubert, Paola M. Soccal, Philippe Eigenmann, Evgeny Zdobnov1, and Laurent Kaiser1
, Thomas Junier1, Daniel Gerlach, Sandra Van Belle, Lara Turin, Samuel Cordey, Kathrin Mühlemann, Nicolas Regamey, John-David Aubert, Paola M. Soccal, Philippe Eigenmann, Evgeny Zdobnov1, and Laurent Kaiser1Table
Characteristics of screened study populations and respiratory samples, Switzerland*
| Type of study (no. enrolled) | Age group | Patient characteristics | Years of study | Type of specimens | PCR | No. (%) positive | Reference |
|---|---|---|---|---|---|---|---|
| Respiratory infection in newborns (243) | <1 y | Nonhospitalized children with initial respiratory episode with cough | 1999–2005 | NPS | HRV-A and HRV-B specific real time for the first 203 and panenterhino for 40 | 36 (15) | (20) |
| Lower respiratory tract infection in hospitalized patients (147) | Adults | Mainly immunocompromised patients with lower respiratory tract complications and comorbidities | 2001–2003 | BAL, NPS | HRV-A and HRV-B specific real time | 16 (11) | (21) |
| Acute respiratory tract infection in children (653) | <17 y | Nonhospitalized children with AOM or pneumonia | 2004–2007 | NPS | Panenterhino | 121 (18) | (22) and ongoing study |
| Lower respiratory tract infection in hospitalized patients (485) | Adults | Mainly immunocompromised patients with lower respiratory tract complications and concurrent illnesses | 2003–2006 | BAL, NPS | Panenterhino | 52 (11) | (21) and ongoing study |
| Acute respiratory tract infection in children (64) | <12 y | Children at an emergency department with fever and acute respiratory symptoms treated with antimicrobial drugs | 2006–2007 | NPS | Panenterhino | 23 (36) | NP |
| Isolation in routine procedures (NA) | Children and adults | Hospitalized patients | 1999–2008 | BAL, NPS | HE culture isolation | NA | NP |
*NPS, nasopharyngeal samples; HRV, human rhinovirus; BAL, bronchoalveolar lavage; AOM, acute otitis media; NP, not published; NA, not available; HE, human embryonic primary fibroblast cell line.
