Role of Rhinovirus C in Apparently Life-Threatening Events in Infants, Spain
Cristina Calvo , M. Luz García, Francisco Pozo, Noelia Reyes, Pilar Pérez-Breña, and Inmaculada Casas
Author affiliations: Hospital Severo Ochoa, Leganés, Madrid, Spain (C. Calvo, M.L. García); National Center for Microbiology, Institute of Health Carlos III, Madrid (F. Pozo, N. Reyes, P. Pérez-Breña, I. Casas).
Figure. Phylogenetic analysis of 5′ noncoding region and viral protein (VP) 4/2 coding region of 9 human rhinoviruses (HRVs) identified in infants with apparently life-threatening events in Spain, November 2004–December 2008. Phylogeny of nucleotide sequences (≈492 bp) was reconstructed with neighbor-joining analysis by applying a Jukes-Cantor model; scale bar indicates nucleotide substitutions per site. Included for reference are sequences belonging to the novel genotype reported previously (QPM and 024, 025, 026 ) and all HRV-A and -B serotypes available in GenBank. Significant bootstrapping is indicated.
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