Skip directly to search Skip directly to A to Z list Skip directly to site content
CDC Home

Volume 16, Number 2—February 2010


Effects of Coronavirus Infections in Children

Nicola PrincipiComments to Author , Samantha Bosis, and Susanna Esposito
Author affiliations: University of Milan, Milan, Italy; and Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico “Ospedale Maggiore Policlinico, Mangiagalli e Regine Elena,” Milan

Main Article


Main studies of the epidemiology and clinical relevance of HCoV-HKU1 in infants and children*

Study Location and period Population No. samples tested No. (%) patients with positive test results Comments
Lau et al. (20) Hong Kong; 
2004 Apr–2005 Mar 629 children with RTIs, 6 mo–5 y; inpatients 629 10 (1.6) 11 patients with URTIs, 1 with pneumonia, 1 with bronchiolitis, 5 with febrile seizures; 3 with underlying disease
Vabret et al. (24) Canada; 
2005 Feb–Mar 83 children with RTIs, <5 y; negative for RSV, influenza A/B, PIV 1–3, adenovirus; inpatients 83 5 (6.0) 3 patients with gastroenteritis, 1 with febrile seizures; mean age 26 mo
Sloots et al. (25) Australia; 
2004 May–Aug 259 children with RTIs, <5 y; inpatients and outpatients 259 10 (3.8) 1 patient with co-infection
Talbot et al. (34) USA; 
2001 Oct–2003 Sep 1,055 children with RTIs, <5 y; inpatients 1,055 4 (0.4) Mild episodes

*HCoV, human coronavirus; RTI, respiratory tract infection; URTI, upper respiratory tract infection; RSV, respiratory syncytial virus; PIV, parainfluenza virus.

Main Article

Top of Page The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO