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Volume 17, Number 10—October 2011

Letter

Complicated Pandemic (H1N1) 2009 during Pregnancy, Taiwan

Wan-Ting Huang, Yu-Fen Hsu, Tsung-Wen Kuo, Wan-Jen Wu, and Jen-Hsiang ChuangComments to Author 
Author affiliations: Taiwan Centers for Disease Control, Taipei, Taiwan

Main Article

Table

Characteristics of women ages 15–49 y who had confirmed pandemic (H1N1) 2009 infection, by pregnancy status, Taiwan, July 1–December 31, 2009*

Characteristic Pregnant, n = 10 Nonpregnant, n = 138 p value†
Age, y 24.5 (22–32) 27.5 (15–49) 0.39
ACIP high-risk condition other than pregnancy
0
28 (20)
0.21
Pneumonia 9 (90) 134 (97) 0.30
ARDS
5 (50)
14 (10)
0.003
Admission to hospital 9 (90) 138 (100) 0.07
Time from symptom onset to
hospitalization, d 2 (0–7) 2 (1–12) 0.78
Length of hospital stay, d
8 (3–47)
5 (0–100)
0.03
Admission to ICU 5 (50) 31 (22) 0.06
Length of ICU stay, d
16 (6–33)
5 (0–83)
0.07
Oseltamivir treatment 9 (90) 135 (98) 0.25
<48 h after illness onset
4 (40)
84‡ (63)
0.19
Mechanical ventilation 5 (50) 19 (14) 0.01
ECMO
3 (30)
1 (1)
<0.001
Death 3 (30) 5 (4) 0.01
Time from illness onset to death, d 16 (2–37) 9 (1–32) 0.57

*Values are median (range) or no. (%). ACIP, Advisory Committee on Immunization Practices; ARDS, acute respiratory distress syndrome; ICU, intensive care unit; ECMO, extracorporeal membrane oxygenation.
†Medians were compared by using Wilcoxon rank-sum test, and proportions were compared by using Fisher exact test.
‡For 4 nonpregnant women, information on date of initiation of oseltamivir treatment was unknown.

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