Emerging Infectious Disease ISSN: 1080-6059

Placental Transmission of Human Parvovirus 4 in Newborns with Hydrops, Taiwan

Mao-Yuan Chen

, Shiu-Ju Yang, and Chien-Ching Hung

Author affiliations: National Taiwan University Hospital, Taipei, Taiwan

Antibody to B19V and PARV4 and detection of viral DNA in mothers and newborns, Taiwan, 2000–2009*

Case and patient	B19V		PARV4
Case and patient	Antibody	DNA	Antibody	DNA
A
Mother	IgM+, IgG+; anti-VP1 and 2	+	IgM+, IgG+	+
Newborn	IgM–, IgG+; anti-VP1 and 2	+	IgM–, IgG+	+
B
Mother	IgM–, IgG+ to VP2 only	–	IgM–, IgG+	+
Newborn	IgM–, IgG+; to VP2 only	–	IgM–, IgG+	+
C
Mother	IgM–, IgG–	–	IgM weak +, IgG–	+
Newborn	IgM–, IgG–	–	IgM–, IgG–	–
D
Mother	IgM–, IgG–	–	IgM weakly positive, IgG–	+
Newborn	IgM–, IgG–	–	IgM–, IgG–	+
E
Mother	IgM weakly positive, IgG+, to VP2 only	–	IgM+, IgG+	+
F
Newborn	IgM–, IgG+; to VP2 only	–	IgM–, IgG+	+ *B19V, parvovirus B19 virus; PARV4, parvovirus 4; Ig, immunoglobulin; +, positive; VP, viral protein; –, negative.

*B19V, parvovirus B19 virus; PARV4, parvovirus 4; Ig, immunoglobulin; +, positive; VP, viral protein; –, negative.