Multidrug-Resistant Tuberculosis, People’s Republic of China, 2007–2009
Guang Xue He1 , Hai Ying Wang1, Martien W. Borgdorff, Dick van Soolingen, Marieke J. van der Werf, Zhi Min Liu, Xue Zheng Li, Hui Guo, Yan Lin Zhao, Jay K. Varma, Christopher P. Tostado, and Susan van den Hof
Author affiliations: Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China (G.X. He, H. Guo, Y.L. Zhao); University of Amsterdam, Amsterdam, the Netherlands (G.X. He, M.W. Borgdorff, M.J. van der Werf, S. van den Hof); Shandong Provincial Tuberculosis Control Center, Jinan, People’s Republic of China (H.Y. Wang, Z.M. Liu, X.Z. Li); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (D. van Soolingen); KNCV Tuberculosis Foundation, The Hague, the Netherlands (M.J. van der Werf, S. van den Hof); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (J.K. Varma); Tsinghua University, Beijing (C.P. Tostado)
Figure 1. The allelic diversity of each VNTR loci (h) and the discriminating power according to the Hunter-Gaston index (HGI) were calculated by using this algorithm (32). MIRU-VNTR, mycobacterial interspersed repetitive unit–variable number of tandem repeats; xi, the frequency of allele i; n, total no. of strains in the scheme; N, total number of strains in the typing scheme; s, total no. of different MIRU-VNTR patterns, nj, no. of strains belonging to the jth type.
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