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Volume 17, Number 11—November 2011

Dispatch

Ultrastructural Characterization of Pandemic (H1N1) 2009 Virus

Cynthia S. GoldsmithComments to Author , Maureen G. Metcalfe, Dominique C. Rollin, Wun-Ju Shieh, Christopher D. Paddock, Xiyan Xu, and Sherif R. Zaki
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Figure 2

Spherical and ovoid extracellular pandemic (H1N1) 2009 virus particles in human lung tissue found in the alveolar space (A) and in a submucosal gland (B). Nucleocapsids and surface projections are visible on some virions. Note the dense material (arrows) associated with the particles. Scale bars = 100 nm. C) Low-power magnification of the aggregation of virus particles seen in panel B, showing virions (box) in the mucus of the submucosal gland. Scale bar = 1 μm. D) Dense tubules (arrow) found in

Figure 2. Spherical and ovoid extracellular pandemic (H1N1) 2009 virus particles in human lung tissue found in the alveolar space (A) and in a submucosal gland (B). Nucleocapsids and surface projections are visible on some virions. Note the dense material (arrows) associated with the particles. Scale bars = 100 nm. C) Low-power magnification of the aggregation of virus particles seen in panel B, showing virions (box) in the mucus of the submucosal gland. Scale bar = 1 μm. D) Dense tubules (arrow) found in the nucleus of an infected cell in alveolar space. Scale bar = 100 nm.

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