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Volume 17, Number 2—February 2011

Research

Leptospirosis in Hawaii, USA, 1999–2008

Alan R. KatzComments to Author , Arlene E. Buchholz, Kialani Hinson, Sarah Y. Park, and Paul V. Effler
Author affiliations: Author affiliations: University of Hawaii, Honolulu, Hawaii, USA (A.R. Katz, K. Hinson); Hawaii State Department of Health, Honolulu (A.E. Buchholz, S.Y. Park, P.V. Effler)

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Table 2

Clinical findings for 198 case-patients with laboratory-confirmed leptospirosis, Hawaii, USA, 1999–2008

Sign, symptoms, and laboratory result
No. (%) patients affected
No. patients with data available
Sign or symptom
Fever 187 (98) 191
Myalgia 162 (88) 185
Headache 156 (87) 179
Nausea 117 (68) 173
Vomiting 101 (59) 172
Arthralgia 73 (46) 157
Diarrhea 79 (46) 171
Backache 50 (34) 146
Jaundice 53 (33) 163
Oliguria or anuria 32 (21) 152
Conjunctival suffusion 30 (19) 156
Nuchal rigidity 23 (14) 159
Pneumonia 13 (8) 154
Hepatosplenomegaly
8 (6)
140
Laboratory results
Renal
Hematuria 78 (73) 107
Proteinuria 71 (68) 105
Elevated creatinine (>1.5 mg/dL) 60 (51) 118
Elevated blood urea nitrogen (>20 mg/dL) 68 (50) 136
Hepatic
Elevated alanine aminotransferase (>40 U/L) 109 (74) 147
Elevated total bilirubin (>1 mg/dL) 85 (63) 134
Hematologic
Thrombocytopenia (<140 × 109/L) 97 (66) 146
Elevated leukocyte count (>10 × 109 cells/L) 74 (48) 155
Decreased hematocrit (<34%) 56 (38) 146

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