Volume 17, Number 3—March 2011
Research
Mycobacterium lentiflavum in Drinking Water Supplies, Australia
Henry M. Marshall
, Robyn Carter, Matthew J. Torbey, Sharri Minion, Carla Tolson, Hanna E. Sidjabat, Flavia Huygens, Megan Hargreaves, and Rachel M. Thomson
, Robyn Carter, Matthew J. Torbey, Sharri Minion, Carla Tolson, Hanna E. Sidjabat, Flavia Huygens, Megan Hargreaves, and Rachel M. ThomsonTable 1
American Thoracic Society/Infectious Diseases Society of America diagnostic criteria for NTM lung disease*
| Clinical criteria |
| Pulmonary symptoms AND |
| Nodular or cavitary opacities on chest radiograph OR |
| Multifocal bronchiectasis with multiple small nodules on high-resolution computerized tomography AND |
| Appropriate exclusion of other diagnoses |
| Microbiologic |
| Positive culture results from at least 2 separate expectorated sputum samples OR |
| Positive culture results from at least 1 bronchial wash or lavage OR |
| Biopsy† showing granulomatous inflammation or acid-fast bacilli and positive culture OR |
| Biopsy† showing granulomatous inflammation or acid-fast
bacilli and one or more culture-positive sputum or bronchial
washings |
| Comments |
| • Risk-benefit of therapy should be considered for each patient • before institution of therapy |
| • Expert consultation should be obtained when NTM are • recovered that are either infrequently encountered or that • usually represent environmental contamination |
| • Patients suspected of having NTM lung disease but who do • not meet the diagnostic criteria should be followed until the • diagnosis is firmly established or excluded |
*Adapted from (2). NTM, nontuberculous mycobacteria.
†Transbronchial or other lung biopsy.
